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KMID : 0371319940470020173
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Journal of the Korean Surgical Society
1994 Volume.47 No. 2 p.173 ~ p.180
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Histologic Multifocality of Breast Carcinomas.
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박희붕
이희대/정우희/오기근/지훈상/김병로/민진식
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Abstract
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Breast cancer multifocality was studied in mastectomy specimens by correlating specimen mammography and histologic techniques. Twenty five mastectomy specimens in 23 patients with breast cancer were included. Of 25 specimens, 7 cases were ductal
carcinoma in situ, one was invastive lobular carcinoma and others were invasive ductal carcinoma. Multifocal cancer foci were present in 5 (29%)mastectomy specimen in 17 patients of invasive ductal carcinoma.
Forty five percent of mulitifocal lesions were licated within 2 cm from the tumor margin and 78% were located within 5 cm. Histologic features of multifocal tumors were intraductal cancers except one area of invastive cancer. Topographical
analysis
showed that all multifocal tumor foci were located in same or adjacent quadrants. Tumor size was not related with multifocality. Three out of seven cases of ductal carcinoma in situ had multifocal cancer foci. We concluded this sesults may be one
of of
the theoretical basis of rational appraoch to the conservative treatment such as quadrantectomy of breast cancer.
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KEYWORD
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